The Japanese yen hit a four-month high, while the Nikkei share index fell 2.5% after the Bank of Japan shocked markets on Tuesday by lifting the cap on bond yield controls.
There is worry about the threat of a huge number of deaths, while the US voiced concern about virus mutations and the economic impacts, both at home and abroad
Stocks in China suffered their biggest fall in seven weeks, while Hong Kong, Tokyo, Sydney and most of Southeast Asia also declined. Indian markets, however, enjoyed a small rise.
The leader manufacturer of chips for automobiles has shut its plant in Beijing after workers caught Covid last week
China's rocky exit from zero-Covid has forced banks and financiers to dust off plans devised to cope with the health crisis, injecting greater of unpredictability into markets
Prime Minister Kishida Fumio announces a five-year plan to prepare the country's armed forces for possible conflict amid rising tensions across the region
Health officials are concerned about rural areas, which are likely to see the return of many family members next month, but have had little exposure to the virus since the pandemic erupted
The US has added dozens of firms to its trade blacklist in a bid to curb China's military, human rights abuses, and block suppliers of the Russian military
US regulators say American auditors have got the green light to inspect the books of US-listed firms in China for the first time, after trial inspections in Hong Kong several months ago
Researchers in Australia have found that sound waves help unlock more hydrogen when electrolysis is performed on water molecules - a discovery that could help reduce the cost of green hydrogen
YMTC is likely to be added to the US Commerce Department's 'Entity List', which bars American firms from selling technology to companies unless they get an export licence, sources have said
Taiwan's National Science and Technology Council says it will fund research on laser-plasma interactions and magnetically confined high-temperature plasmas, following US discovery